Chagas' disease, caused by the protozoan parasite Trypanosoma cruzi is a lifelong infection if left untreated. An estimated 300,000 people living in the United States are currently infected, and 20 to 30% of these will develop symptomatic, potentially life-threatening Chagas' disease. Many of these infections are not recognized. Treatment with anti-trypanosomal drugs are always recommended for acute disease, reactivation, and chronic disease in children less than 18 years of age. During this lecture, Dr. Natasha Hochberg, Associate Professor in the Department of Medicine at the Boston University School of Medicine and School of Public Health, will discuss treatment, who to treat, what treatments are available, and how to manage adverse reactions. She will bring her vast experience diagnosing and treating patients with Chagas disease in Boston.